Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDM45547.1Lactoylglutathione lyase. (128 aa)    
Predicted Functional Partners:
EDM45548.1
COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
  0.890
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
     
  0.888
EDM43717.1
Putative chorismate mutase; COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.
    
  0.772
EDM44743.1
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
     
  0.726
EDM43467.1
Metallo-beta-lactamase superfamily protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
    
  0.711
EDM45006.1
Rhodanese-like protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
    
  0.711
EDM45546.1
COG2314 Predicted membrane protein.
       0.609
EDM45106.1
COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.
     
  0.515
EDM43089.1
Probable oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases.
     
  0.511
EDM42893.1
COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
   
  0.442
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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