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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM45557.1Bifunctional protein: riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family. (310 aa)    
Predicted Functional Partners:
truB
Pseudouridylate synthase (pseudouridine synthase); Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.945
ribH
Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.923
cmk
COG0283 Cytidylate kinase.
 
  
 0.914
EDM43279.1
Riboflavin biosynthesis protein ribD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
 
 0.894
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.850
EDM43487.1
B-glycosyltransferase, glycosyltransferase family 2 protein; COG1216 Predicted glycosyltransferases.
      0.830
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.814
EDM45556.1
Gamma-glutamyl carboxylase-like protein.
       0.791
EDM44862.1
Phosphoenolpyruvate-protein phosphotransferase; COG3412 Uncharacterized protein conserved in bacteria; Belongs to the PEP-utilizing enzyme family.
    
   0.790
EDM45555.1
Hypothetical protein.
       0.773
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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