close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM45602.1Sensory transduction histidine kinase; COG0457 FOG: TPR repeat. (669 aa)    
Predicted Functional Partners:
EDM45601.1
Two component transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  0.974
EDM45619.1
COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  0.889
EDM43578.1
COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  0.889
EDM43748.1
Two component transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
  0.889
EDM44613.1
COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  0.888
EDM45173.1
Sensor histidine kinase; COG2202 FOG: PAS/PAC domain.
 
  
 0.683
EDM44982.1
Transcriptional regulator, sigma-54-related protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
    
 0.674
EDM45221.1
COG0642 Signal transduction histidine kinase.
  
 0.634
EDM43866.1
Two-component system sensor histidine kinase; COG0642 Signal transduction histidine kinase.
  
 0.624
EDM44305.1
Hypothetical protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
  0.606
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.