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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM45661.1COG1331 Highly conserved protein containing a thioredoxin domain. (703 aa)    
Predicted Functional Partners:
EDM45662.1
Mechanosensitive ion channel family protein; COG0668 Small-conductance mechanosensitive channel.
       0.773
EDM42983.1
Tyrosine-protein kinase; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.
    
  0.642
EDM43003.1
Putative EPS related membrane protein; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.
    
  0.642
EDM45659.1
Hypothetical protein.
   
   0.627
thyA
Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.581
EDM43434.1
Hypothetical protein; COG0405 Gamma-glutamyltransferase.
  
  
  0.533
EDM45660.1
COG0694 Thioredoxin-like proteins and domains.
       0.532
EDM45707.1
Deoxyguanosine kinase/deoxyadenosine kinase subunit; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
    
  0.471
EDM44948.1
Lipase/acylhydrolase family protein; COG2755 Lysophospholipase L1 and related esterases.
    
 
 0.422
EDM45720.1
Hypothetical protein.
   
   0.421
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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