STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (306 aa)    
Predicted Functional Partners:
EDM45740.1
Bifunctional protein: aspartokinase I; COG0460 Homoserine dehydrogenase.
 
 0.999
EDM45744.1
COG0527 Aspartokinases.
 
 0.999
EDM45746.1
COG0498 Threonine synthase.
 
 0.999
EDM45739.1
COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family.
  
 0.998
EDM45742.1
Methionine synthase I; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.877
EDM45741.1
Methionine synthase I, homocysteine S-methyltransferase; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
    
 0.873
EDM45131.1
COG0739 Membrane proteins related to metalloendopeptidases.
    
  0.861
EDM45737.1
COG2873 O-acetylhomoserine sulfhydrylase.
    
  0.839
EDM43517.1
4-amino-4-deoxychorismate lyase, putative; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
 
 0.811
EDM44877.1
Branched-chain-amino-acid transaminase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.811
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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