close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM43641.1COG0642 Signal transduction histidine kinase. (381 aa)    
Predicted Functional Partners:
EDM44568.1
COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
  
 
 0.822
EDM45173.1
Sensor histidine kinase; COG2202 FOG: PAS/PAC domain.
 
 
0.808
EDM43604.1
(pyruvate) Oxoisovalerate Dehydrogenase Alpha and Beta Fusion; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
    
 0.792
EDM43022.1
Transketolase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
    
 0.792
EDM43107.1
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
    
 0.792
EDM44316.1
Two-component response regulator; COG0457 FOG: TPR repeat.
   
 0.767
EDM44223.1
Hypothetical protein; COG2067 Long-chain fatty acid transport protein.
  
     0.760
EDM43316.1
Hypothetical protein; COG2183 Transcriptional accessory protein.
  
 
 0.757
EDM44982.1
Transcriptional regulator, sigma-54-related protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
  
 
 0.746
EDM43669.1
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  0.737
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (36%) [HD]