Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDM43688.1Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. (105 aa)    
Predicted Functional Partners:
EDM43444.1
COG0492 Thioredoxin reductase.
 0.970
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.805
EDM45577.1
COG0209 Ribonucleotide reductase, alpha subunit.
  
 0.803
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.756
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
    0.749
EDM45576.1
COG0209 Ribonucleotide reductase, alpha subunit.
  
 
 0.682
EDM45200.1
Hypothetical protein; COG2866 Predicted carboxypeptidase.
    
   0.632
EDM43394.1
Alkyl hydroperoxide reductase, F52a subunit; COG0492 Thioredoxin reductase.
  
  0.628
EDM45159.1
Pyridine nucleotide-disulphide oxidoreductase, putative; COG0492 Thioredoxin reductase.
  
  0.628
EDM43678.1
COG0492 Thioredoxin reductase.
  
  0.628
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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