| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDM43686.1 | EDM43915.1 | SCB49_08848 | SCB49_09995 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.715 |
| EDM43686.1 | EDM44532.1 | SCB49_08848 | SCB49_13210 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.597 |
| EDM43686.1 | EDM44791.1 | SCB49_08848 | SCB49_14505 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.999 |
| EDM43686.1 | EDM45156.1 | SCB49_08848 | SCB49_03509 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.602 |
| EDM43686.1 | dnaG | SCB49_08848 | SCB49_09155 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | 0.660 |
| EDM43686.1 | guaB | SCB49_08848 | SCB49_11809 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.769 |
| EDM43686.1 | nusA | SCB49_08848 | SCB49_04620 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.423 |
| EDM43686.1 | polA | SCB49_08848 | SCB49_04675 | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.841 |
| EDM43915.1 | EDM43686.1 | SCB49_09995 | SCB49_08848 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | 0.715 |
| EDM43915.1 | EDM44791.1 | SCB49_09995 | SCB49_14505 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.516 |
| EDM43915.1 | dnaG | SCB49_09995 | SCB49_09155 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | 0.997 |
| EDM43915.1 | polA | SCB49_09995 | SCB49_04675 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.628 |
| EDM43915.1 | trmD | SCB49_09995 | SCB49_01027 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.574 |
| EDM44532.1 | EDM43686.1 | SCB49_13210 | SCB49_08848 | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | 0.597 |
| EDM44532.1 | EDM44791.1 | SCB49_13210 | SCB49_14505 | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.647 |
| EDM44532.1 | dnaG | SCB49_13210 | SCB49_09155 | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | 0.894 |
| EDM44532.1 | nusA | SCB49_13210 | SCB49_04620 | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.831 |
| EDM44532.1 | polA | SCB49_13210 | SCB49_04675 | RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.438 |
| EDM44791.1 | EDM43686.1 | SCB49_14505 | SCB49_08848 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG2176 DNA polymerase III, alpha subunit (gram-positive type). | 0.999 |
| EDM44791.1 | EDM43915.1 | SCB49_14505 | SCB49_09995 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.516 |
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