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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM43749.1NH(3)-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (264 aa)    
Predicted Functional Partners:
nadD-2
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.742
EDM43949.1
Competence-damage inducible protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
    
 0.700
EDM44069.1
Hypothetical protein; COG1056 Nicotinamide mononucleotide adenylyltransferase.
  
 
 0.689
EDM43200.1
COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
    
 0.689
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.682
EDM45201.1
Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.
 
 
 0.670
EDM44256.1
NadR-like protein; COG3172 Predicted ATPase/kinase involved in NAD metabolism.
     
 0.660
cobB
COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
    
 0.632
EDM43972.1
Phosphohydrolase (MutT/nudix family protein); COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
  
 
 0.623
EDM44255.1
Hypothetical protein; COG1163 Predicted GTPase.
     
 0.604
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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