STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM43924.1Hypothetical protein; COG2194 Predicted membrane-associated, metal-dependent hydrolase. (562 aa)    
Predicted Functional Partners:
EDM43089.1
Probable oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases.
  
 
 0.773
EDM44685.1
Putative adenylate/guanylate cyclase; COG1177 ABC-type spermidine/putrescine transport system, permease component II.
    
 
 0.658
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
   
 
  0.547
EDM43925.1
COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.
       0.544
EDM43082.1
Possible oxidoreductase, Fe-S subunit; COG0247 Fe-S oxidoreductase.
  
 
  0.527
EDM43084.1
Fe-S oxidoreductase, possible dehydrogenase subunit; COG0247 Fe-S oxidoreductase.
  
 
  0.527
EDM44211.1
COG1785 Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
 
 0.514
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
     
  0.510
hisC
COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
  0.510
EDM43275.1
Aquaporin Z; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.510
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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