STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM43956.1COG0438 Glycosyltransferase. (409 aa)    
Predicted Functional Partners:
EDM43955.1
BNR repeat, putative.
       0.723
EDM43957.1
COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
 
     0.593
EDM43958.1
Hypothetical protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.
       0.509
EDM44461.1
GGDEF domain protein; COG3292 Predicted periplasmic ligand-binding sensor domain.
     
  0.498
EDM43467.1
Metallo-beta-lactamase superfamily protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
     
  0.454
EDM45006.1
Rhodanese-like protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
     
  0.454
EDM45310.1
Hydrolase; COG0491 Zn-dependent hydrolases, including glyoxylases.
     
  0.454
EDM43597.1
Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases.
     
  0.448
rimO
2-methylthioadenine synthetase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
       0.425
EDM44548.1
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
     0.425
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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