Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
EDM43961.1Hypothetical protein; COG1466 DNA polymerase III, delta subunit. (335 aa)    
Predicted Functional Partners:
EDM43686.1
COG2176 DNA polymerase III, alpha subunit (gram-positive type).
  
 0.995
EDM44791.1
DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.987
EDM45344.1
Putative DNA polymerase III, delta subunit; COG0470 ATPase involved in DNA replication.
 
 
 0.964
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.943
EDM44090.1
Hypothetical protein.
   
 0.934
EDM43258.1
COG2176 DNA polymerase III, alpha subunit (gram-positive type).
 
  
 0.906
EDM42916.1
COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
    
 0.892
EDM43946.1
COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
    
 0.889
EDM43915.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
   
 0.781
EDM43960.1
Hypothetical protein.
 
     0.780
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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