STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM43971.1Putative O-succinylbenzoate--CoA ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (356 aa)    
Predicted Functional Partners:
EDM43969.1
Chloromuconate cycloisomerase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.
 
  0.998
EDM45380.1
Polyunsaturated fatty acid synthase PfaA; COG3321 Polyketide synthase modules and related proteins.
  
 0.987
menB
Naphthoate synthase (dihydroxynaphtoic acid synthetase); Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
  
 0.961
EDM45378.1
Hypothetical protein; COG3321 Polyketide synthase modules and related proteins; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.895
EDM43597.1
Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases.
  
 0.887
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.886
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.885
EDM43113.1
COG0236 Acyl carrier protein.
  
 0.885
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
  
 0.873
EDM45379.1
Polyunsaturated fatty acid synthase PfaA; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 0.841
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.