Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM43980.1Ferric uptake regulator, FUR family protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. (127 aa)    
Predicted Functional Partners:
EDM43977.1
Hypothetical protein.
 
     0.690
EDM43978.1
Hypothetical protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.
 
     0.658
EDM43979.1
COG1131 ABC-type multidrug transport system, ATPase component.
 
     0.618
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.586
EDM43939.1
COG1832 Predicted CoA-binding protein.
 
    0.578
EDM44143.1
COG1629 Outer membrane receptor proteins, mostly Fe transport.
 
     0.574
EDM44145.1
Hypothetical protein.
 
     0.552
EDM44444.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.466
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.437
EDM43150.1
Hypothetical protein.
  
     0.415
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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