Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM43994.1COG1680 Beta-lactamase class C and other penicillin binding proteins. (415 aa)    
Predicted Functional Partners:
guaB
Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.619
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
     
 0.514
EDM43993.1
Hypothetical protein.
       0.493
EDM43426.1
Oligopeptide ABC transporter, solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.
  
  
  0.480
EDM43746.1
COG0222 Ribosomal protein L7/L12.
     
  0.480
EDM45285.1
Multiple sugar-binding ABC transporter, ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.
     
  0.465
EDM45421.1
ABC transporter, ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.
     
  0.463
EDM43878.1
beta-N-acetylglucosaminidase; COG1472 Beta-glucosidase-related glycosidases.
 
 
  0.461
EDM43995.1
Hypothetical protein; COG0457 FOG: TPR repeat.
       0.457
EDM44355.1
Putative carboxypeptidase; COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF.
 
  
  0.436
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (26%) [HD]