STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM43996.1Hypothetical protein. (215 aa)    
Predicted Functional Partners:
EDM43995.1
Hypothetical protein; COG0457 FOG: TPR repeat.
       0.459
EDM43997.1
Hypothetical protein.
       0.421
EDM43998.1
Hypothetical protein.
       0.421
EDM43999.1
Hypothetical protein.
       0.421
EDM44000.1
Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]
       0.421
EDM44001.1
Heat shock protein DnaJ-like protein; COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain.
       0.421
EDM44002.1
Hypothetical protein; COG0419 ATPase involved in DNA repair.
       0.414
EDM44003.1
COG0739 Membrane proteins related to metalloendopeptidases.
       0.414
EDM44004.1
Heat shock protein Hsp70; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
       0.414
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.