| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDM43286.1 | EDM44032.1 | SCB49_00987 | SCB49_10592 | Hypothetical protein; COG0313 Predicted methyltransferases. | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.562 |
| EDM43324.1 | EDM44032.1 | SCB49_01177 | SCB49_10592 | Elongation factor Tu; COG0690 Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.606 |
| EDM43324.1 | EDM44765.1 | SCB49_01177 | SCB49_14375 | Elongation factor Tu; COG0690 Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. | COG1862 Preprotein translocase subunit YajC. | 0.792 |
| EDM43324.1 | ffh | SCB49_01177 | SCB49_09755 | Elongation factor Tu; COG0690 Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.897 |
| EDM43324.1 | ftsY | SCB49_01177 | SCB49_10197 | Elongation factor Tu; COG0690 Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.888 |
| EDM43324.1 | secA-2 | SCB49_01177 | SCB49_01919 | Elongation factor Tu; COG0690 Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. | Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.965 |
| EDM43324.1 | secY | SCB49_01177 | SCB49_09600 | Elongation factor Tu; COG0690 Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
| EDM43324.1 | yidC | SCB49_01177 | SCB49_00475 | Elongation factor Tu; COG0690 Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. | Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.911 |
| EDM44032.1 | EDM43286.1 | SCB49_10592 | SCB49_00987 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Hypothetical protein; COG0313 Predicted methyltransferases. | 0.562 |
| EDM44032.1 | EDM43324.1 | SCB49_10592 | SCB49_01177 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Elongation factor Tu; COG0690 Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. | 0.606 |
| EDM44032.1 | EDM44033.1 | SCB49_10592 | SCB49_10597 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Oligopeptidase (protease II); COG1770 Protease II. | 0.655 |
| EDM44032.1 | EDM44765.1 | SCB49_10592 | SCB49_14375 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | COG1862 Preprotein translocase subunit YajC. | 0.594 |
| EDM44032.1 | ffh | SCB49_10592 | SCB49_09755 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.560 |
| EDM44032.1 | ftsY | SCB49_10592 | SCB49_10197 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.557 |
| EDM44032.1 | recR | SCB49_10592 | SCB49_10142 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.904 |
| EDM44032.1 | secA-2 | SCB49_10592 | SCB49_01919 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.592 |
| EDM44032.1 | secY | SCB49_10592 | SCB49_09600 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.563 |
| EDM44032.1 | yidC | SCB49_10592 | SCB49_00475 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.559 |
| EDM44033.1 | EDM44032.1 | SCB49_10597 | SCB49_10592 | Oligopeptidase (protease II); COG1770 Protease II. | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.655 |
| EDM44765.1 | EDM43324.1 | SCB49_14375 | SCB49_01177 | COG1862 Preprotein translocase subunit YajC. | Elongation factor Tu; COG0690 Preprotein translocase subunit SecE; Belongs to the SecE/SEC61-gamma family. | 0.792 |
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