STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM44055.1Hydrolase, NUDIX family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (213 aa)    
Predicted Functional Partners:
nnrD
Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
  
 0.960
rnr
Exoribonuclease II; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
 0.827
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
   
  0.764
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.727
EDM44056.1
Hypothetical protein.
 
     0.727
EDM45707.1
Deoxyguanosine kinase/deoxyadenosine kinase subunit; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
    
 0.696
EDM43992.1
Tetratricopeptide repeat family protein; COG0457 FOG: TPR repeat.
   
 0.676
EDM43949.1
Competence-damage inducible protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
    
  0.670
EDM43549.1
COG0513 Superfamily II DNA and RNA helicases.
    
  0.669
EDM43863.1
RNA helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
    
  0.669
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (16%) [HD]