Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDM44074.1COG0044 Dihydroorotase and related cyclic amidohydrolases. (417 aa)    
Predicted Functional Partners:
pyrB
COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 0.998
EDM43153.1
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 0.961
carA
COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
 
 0.938
EDM43417.1
COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ).
 
 0.923
EDM44079.1
COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase.
 
 
 0.893
EDM43906.1
COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase.
 
 
 0.876
EDM43662.1
COG0044 Dihydroorotase and related cyclic amidohydrolases.
  
  
 
0.847
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.840
EDM44072.1
Phospholipase/carboxylesterase family protein; COG0400 Predicted esterase.
   
   0.807
pyrF
COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.790
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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