| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDM43089.1 | EDM43117.1 | SCB49_12729 | SCB49_11599 | Probable oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases. | COG0818 Diacylglycerol kinase. | 0.632 |
| EDM43117.1 | EDM43089.1 | SCB49_11599 | SCB49_12729 | COG0818 Diacylglycerol kinase. | Probable oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases. | 0.632 |
| EDM43117.1 | EDM43193.1 | SCB49_11599 | SCB49_11979 | COG0818 Diacylglycerol kinase. | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.634 |
| EDM43117.1 | EDM44773.1 | SCB49_11599 | SCB49_14415 | COG0818 Diacylglycerol kinase. | GTP diphosphokinase (guanosine 3',5'-polyphosphate synthase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.675 |
| EDM43117.1 | dut | SCB49_11599 | SCB49_05672 | COG0818 Diacylglycerol kinase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.631 |
| EDM43117.1 | gmk | SCB49_11599 | SCB49_05105 | COG0818 Diacylglycerol kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.631 |
| EDM43117.1 | murG | SCB49_11599 | SCB49_09240 | COG0818 Diacylglycerol kinase. | N-acetylglucosaminyl transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.640 |
| EDM43117.1 | pyrG | SCB49_11599 | SCB49_00480 | COG0818 Diacylglycerol kinase. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.659 |
| EDM43117.1 | pyrH | SCB49_11599 | SCB49_07412 | COG0818 Diacylglycerol kinase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.645 |
| EDM43117.1 | tpx | SCB49_11599 | SCB49_11604 | COG0818 Diacylglycerol kinase. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. | 0.792 |
| EDM43117.1 | ybeY | SCB49_11599 | SCB49_06027 | COG0818 Diacylglycerol kinase. | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.731 |
| EDM43193.1 | EDM43117.1 | SCB49_11979 | SCB49_11599 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | COG0818 Diacylglycerol kinase. | 0.634 |
| EDM43193.1 | EDM44773.1 | SCB49_11979 | SCB49_14415 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GTP diphosphokinase (guanosine 3',5'-polyphosphate synthase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.639 |
| EDM43193.1 | dut | SCB49_11979 | SCB49_05672 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.749 |
| EDM43193.1 | gmk | SCB49_11979 | SCB49_05105 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.645 |
| EDM43193.1 | pyrG | SCB49_11979 | SCB49_00480 | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.675 |
| EDM44773.1 | EDM43117.1 | SCB49_14415 | SCB49_11599 | GTP diphosphokinase (guanosine 3',5'-polyphosphate synthase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | COG0818 Diacylglycerol kinase. | 0.675 |
| EDM44773.1 | EDM43193.1 | SCB49_14415 | SCB49_11979 | GTP diphosphokinase (guanosine 3',5'-polyphosphate synthase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.639 |
| EDM44773.1 | gmk | SCB49_14415 | SCB49_05105 | GTP diphosphokinase (guanosine 3',5'-polyphosphate synthase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.646 |
| dut | EDM43117.1 | SCB49_05672 | SCB49_11599 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | COG0818 Diacylglycerol kinase. | 0.631 |
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