STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM43144.1COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (474 aa)    
Predicted Functional Partners:
EDM45739.1
COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family.
  
 
 0.947
EDM45740.1
Bifunctional protein: aspartokinase I; COG0460 Homoserine dehydrogenase.
  
 
 0.947
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.833
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.736
EDM44547.1
COG0440 Acetolactate synthase, small (regulatory) subunit.
  
 
 0.690
gcvT-2
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.686
EDM45744.1
COG0527 Aspartokinases.
  
 
 0.681
EDM44435.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.677
EDM45746.1
COG0498 Threonine synthase.
   
 
 0.675
EDM44546.1
Putative acetolactate synthase large subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].
   
 
 0.639
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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