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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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gene co-occurrence
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[Homology]
Score
EDM43170.1Aconitate hydratase 2; COG1049 Aconitase B. (935 aa)    
Predicted Functional Partners:
EDM43846.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.924
sucC
succinate--CoA ligase, ADP-forming (succinyl-CoA synthetase, beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.922
EDM43171.1
Aconitate hydratase; COG1048 Aconitase A.
    
 0.919
EDM43931.1
COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
   
 
 0.850
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.842
EDM44267.1
COG0281 Malic enzyme.
  
 
 0.825
EDM43712.1
COG3278 Cbb3-type cytochrome oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family.
   
    0.825
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
    
 0.799
EDM45599.1
COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
   
  
 0.791
EDM44559.1
succinate--CoA ligase, ADP-forming (succinyl-CoA synthetase, alpha subunit); COG0074 Succinyl-CoA synthetase, alpha subunit.
  
 
 0.616
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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