Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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sucCsuccinate--CoA ligase, ADP-forming (succinyl-CoA synthetase, beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)    
Predicted Functional Partners:
EDM44560.1
succinate--CoA ligase, ADP-forming (succinyl-CoA synthetase, alpha subunit); COG0074 Succinyl-CoA synthetase, alpha subunit.
 0.999
EDM44559.1
succinate--CoA ligase, ADP-forming (succinyl-CoA synthetase, alpha subunit); COG0074 Succinyl-CoA synthetase, alpha subunit.
 
 0.996
EDM45599.1
COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
 
 0.989
sdhA
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 0.972
EDM43846.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 0.966
EDM44339.1
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.964
EDM44267.1
COG0281 Malic enzyme.
  
 
 0.953
EDM43787.1
Putative acetyl-CoA hydrolase/transferase; COG0427 Acetyl-CoA hydrolase.
   
 0.935
EDM45600.1
Dihydrolipoyllysine-residue succinyltransferase, component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
  
 0.924
EDM44220.1
Dihydrolipoyllysine-residue acetyltransferase (dihydrolipoamide S-acetyltransferase); COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
  
 0.923
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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