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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBCOG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. (224 aa)    
Predicted Functional Partners:
EDM44269.1
COG2124 Cytochrome P450.
    
  0.834
EDM44414.1
COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
    
 
 0.792
EDM44256.1
NadR-like protein; COG3172 Predicted ATPase/kinase involved in NAD metabolism.
   
 
  0.771
EDM44255.1
Hypothetical protein; COG1163 Predicted GTPase.
   
 
  0.717
EDM43949.1
Competence-damage inducible protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
    
 0.693
EDM43253.1
Oxidoreductase, Gfo/Idh/MocA family protein; COG0673 Predicted dehydrogenases and related proteins.
    
  0.689
nadD-2
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.670
EDM44124.1
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
    
 0.636
EDM44125.1
Propionyl CoA synthase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
    
 0.636
EDM43749.1
NH(3)-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.632
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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