STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM44466.1Chaperone with DnaK; COG2214 DnaJ-class molecular chaperone. (149 aa)    
Predicted Functional Partners:
EDM43937.1
Heat shock protein 90; COG0326 Molecular chaperone, HSP90 family.
  
 0.921
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.880
EDM43472.1
COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
   
 0.872
EDM44691.1
COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
   
 0.872
EDM44934.1
COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
  
  0.867
EDM44932.1
Heat shock protein Hsp70; COG0443 Molecular chaperone.
  
  0.866
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.857
EDM44004.1
Heat shock protein Hsp70; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
   
  0.846
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
  0.846
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
  0.840
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.