Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM44487.1Iron-containing alcohol dehydrogenase; COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family. (385 aa)    
Predicted Functional Partners:
EDM43399.1
ARA1; COG0656 Aldo/keto reductases, related to diketogulonate reductase.
  
 
 0.825
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
  
    0.774
EDM44489.1
COG1309 Transcriptional regulator.
 
     0.757
EDM44488.1
Nitroreductase family protein; COG0778 Nitroreductase.
  
    0.657
EDM44504.1
COG1454 Alcohol dehydrogenase, class IV.
  
  
0.656
EDM44267.1
COG0281 Malic enzyme.
     
 0.629
EDM44435.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
     
  0.516
eno
Phosphopyruvate hydratase (enolase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
  0.516
EDM44486.1
Hypothetical protein.
       0.428
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
Server load: low (20%) [HD]