STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM44498.1COG4222 Uncharacterized protein conserved in bacteria. (372 aa)    
Predicted Functional Partners:
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
     
  0.875
guaB
Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.728
EDM44238.1
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
     
  0.537
EDM45591.1
COG0038 Chloride channel protein EriC.
     
  0.537
folE-3
COG0302 GTP cyclohydrolase I.
    
  0.503
EDM43082.1
Possible oxidoreductase, Fe-S subunit; COG0247 Fe-S oxidoreductase.
     
  0.499
EDM43084.1
Fe-S oxidoreductase, possible dehydrogenase subunit; COG0247 Fe-S oxidoreductase.
     
  0.499
EDM43089.1
Probable oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases.
     
  0.499
EDM44495.1
ABC transporter related protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.
       0.486
EDM44496.1
Hypothetical protein; COG0577 ABC-type antimicrobial peptide transport system, permease component.
       0.486
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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