STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM44656.1COG0308 Aminopeptidase N. (560 aa)    
Predicted Functional Partners:
EDM44657.1
COG4430 Uncharacterized protein conserved in bacteria.
       0.706
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.601
EDM44655.1
Peptidase M28; COG2234 Predicted aminopeptidases.
   
  0.565
EDM44022.1
COG0308 Aminopeptidase N.
  
  
 
0.554
EDM42930.1
Putative aminoacyl-histidine dipeptidase; COG2195 Di- and tripeptidases.
     
 0.549
EDM45240.1
Hypothetical protein.
 
     0.540
EDM43973.1
Neutral zinc metallopeptidase, M1 family protein; COG0308 Aminopeptidase N.
  
  
 
0.473
EDM44654.1
Hypothetical protein; COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N).
       0.431
gshB
COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.
  
  
  0.412
EDM45511.1
Hypothetical protein.
  
     0.403
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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