STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDM44685.1Putative adenylate/guanylate cyclase; COG1177 ABC-type spermidine/putrescine transport system, permease component II. (373 aa)    
Predicted Functional Partners:
EDM45174.1
Transcriptional regulator; COG0784 FOG: CheY-like receiver.
 
 0.961
EDM45221.1
COG0642 Signal transduction histidine kinase.
   
 0.927
EDM42881.1
Sensor histidine kinase/GAF domain hybrid protein; COG2203 FOG: GAF domain.
 
 0.893
ribB
Bifunctional protein: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.875
EDM45534.1
Hybrid sensory kinase; COG0642 Signal transduction histidine kinase.
 
 
 0.844
EDM45535.1
Hypothetical protein; COG1100 GTPase SAR1 and related small G proteins.
  
 
 0.822
EDM44338.1
Histidine kinase; COG0642 Signal transduction histidine kinase.
   
 0.818
EDM43866.1
Two-component system sensor histidine kinase; COG0642 Signal transduction histidine kinase.
   
 0.818
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.790
EDM44430.1
Adenylate cyclase; COG2954 Uncharacterized protein conserved in bacteria.
     
  0.788
Your Current Organism:
unidentified eubacterium SCB49
NCBI taxonomy Id: 50743
Other names: u. eubacterium SCB49
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