node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDM42931.1 | EDM43417.1 | SCB49_11562 | SCB49_00170 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | 0.626 |
EDM42931.1 | adk | SCB49_11562 | SCB49_04150 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.902 |
EDM42931.1 | guaA | SCB49_11562 | SCB49_00510 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.877 |
EDM42931.1 | guaB | SCB49_11562 | SCB49_11809 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.902 |
EDM42931.1 | purA | SCB49_11562 | SCB49_14425 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.992 |
EDM42931.1 | purC-2 | SCB49_11562 | SCB49_14485 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.979 |
EDM42931.1 | purH | SCB49_11562 | SCB49_02879 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.972 |
EDM42931.1 | purL | SCB49_11562 | SCB49_13520 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
EDM43417.1 | EDM42931.1 | SCB49_00170 | SCB49_11562 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.626 |
EDM43417.1 | EDM45739.1 | SCB49_00170 | SCB49_08017 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | 0.713 |
EDM43417.1 | EDM45740.1 | SCB49_00170 | SCB49_08022 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | Bifunctional protein: aspartokinase I; COG0460 Homoserine dehydrogenase. | 0.713 |
EDM43417.1 | guaA | SCB49_00170 | SCB49_00510 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.807 |
EDM43417.1 | guaB | SCB49_00170 | SCB49_11809 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.685 |
EDM43417.1 | purA | SCB49_00170 | SCB49_14425 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.819 |
EDM43417.1 | purH | SCB49_00170 | SCB49_02879 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.679 |
EDM43417.1 | purL | SCB49_00170 | SCB49_13520 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.865 |
EDM45739.1 | EDM43417.1 | SCB49_08017 | SCB49_00170 | COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). | 0.713 |
EDM45739.1 | EDM45740.1 | SCB49_08017 | SCB49_08022 | COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | Bifunctional protein: aspartokinase I; COG0460 Homoserine dehydrogenase. | 0.999 |
EDM45739.1 | adk | SCB49_08017 | SCB49_04150 | COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.615 |
EDM45739.1 | guaA | SCB49_08017 | SCB49_00510 | COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.966 |