STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGRI_068880RBR-type E3 ubiquitin transferase. (662 aa)    
Predicted Functional Partners:
PGRI_007520
Uncharacterized protein.
     
 0.695
PGRI_021060
Translation elongation/initiation factor/Ribosomal, beta-barrel.
   
 
 0.642
PGRI_022740
Molybdenum cofactor biosynthesis, MoeB.
   
 
  0.521
PGRI_045680
Zinc finger, CCCH-type.
   
 
  0.520
PGRI_009750
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
     
 0.508
PGRI_046550
Aldolase-type TIM barrel.
    
 
 0.470
PGRI_086560
Peptide chain release factor eRF1/aRF1.
    
 
 0.463
PGRI_046330
Fps/Fes/Fer/CIP4 homology.
    
 
 0.445
PGRI_070640
ATPase, F1 complex, OSCP/delta subunit.
    
   0.444
PGRI_064870
HECT domain-containing protein.
     
 0.425
Your Current Organism:
Penicillium griseofulvum
NCBI taxonomy Id: 5078
Other names: CBS 185.27, P. griseofulvum, Penicillium patulum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.