STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGRI_001690Winged helix-turn-helix transcription repressor DNA-binding. (1093 aa)    
Predicted Functional Partners:
PGRI_039830
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.950
PGRI_038950
Histone deacetylase superfamily.
   
 0.950
PGRI_056020
Histone-binding protein RBBP4.
   
 0.887
PGRI_022720
Sec1-like protein; Belongs to the STXBP/unc-18/SEC1 family.
 
   
  0.885
PGRI_044770
Histone H3; Belongs to the histone H3 family.
    
 0.873
PGRI_068110
Histone-fold.
    
 0.873
PGRI_001270
SNF2-related protein.
   
 0.869
PGRI_045350
Histone H2A; Belongs to the histone H2A family.
    
 0.812
PGRI_045340
Histone H2B; Belongs to the histone H2B family.
    
 0.776
PGRI_022830
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.758
Your Current Organism:
Penicillium griseofulvum
NCBI taxonomy Id: 5078
Other names: CBS 185.27, P. griseofulvum, Penicillium patulum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.