STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_0059PFAM: Rieske [2Fe-2S] iron-sulphur domain; KEGG: ccs:CCNA_00066 Rieske (2Fe-2S) domain protein. (121 aa)    
Predicted Functional Partners:
Cseg_0047
Siroheme synthase; KEGG: ccs:CCNA_00024 uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; TIGRFAM: siroheme synthase; PFAM: Sirohaem synthase, dimerisation domain.
  
  
 0.816
Cseg_0060
PFAM: YCII-related; KEGG: ccs:CCNA_00067 cytosolic protein.
       0.791
gpsA
KEGG: ccs:CCNA_00068 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
       0.788
Cseg_0159
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ccs:CCNA_03640 ferredoxin NAD(+) reductase.
  
 
 0.780
Cseg_2058
KEGG: cak:Caul_2956 nitrite reductase (NAD(P)H), large subunit; TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region.
  
 
 0.780
Cseg_3012
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pzu:PHZ_c0214 ferredoxin reductase.
  
 
 0.780
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.762
Cseg_0064
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
 0.645
Cseg_2514
TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; YHS domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: pzu:PHZ_c1472 copper-translocating P-type ATPase; SMART: TRASH domain protein.
   
   0.645
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
     
 0.588
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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