STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (220 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.960
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.957
Cseg_1324
PFAM: CinA domain protein; KEGG: cak:Caul_3350 CinA domain-containing protein; Belongs to the CinA family.
  
 
 0.950
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
 
 0.949
Cseg_3424
TIGRFAM: nicotinate-nucleotide pyrophosphorylase; KEGG: ccs:CCNA_03009 nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
    
 0.945
Cseg_3705
Cytidyltransferase-related domain protein; KEGG: xcv:XCV0734 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; TIGRFAM: cytidyltransferase-related domain protein; PFAM: NUDIX hydrolase; cytidylyltransferase; Belongs to the Nudix hydrolase family.
  
 
 0.944
Cseg_3704
KEGG: sml:Smlt0260 putative nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; Belongs to the NAPRTase family.
  
 
 0.942
Cseg_0618
NAD(P)(+) transhydrogenase (AB-specific); KEGG: ccs:CCNA_03414 NAD(P) transhydrogenase alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein.
     
 0.906
Cseg_0619
KEGG: ccs:CCNA_03413 NAD(P) transhydrogenase alpha subunit.
     
 0.906
Cseg_3891
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: ccs:CCNA_00267 MutT-like protein; Belongs to the Nudix hydrolase family.
     
 0.906
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.