STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_0578Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (138 aa)    
Predicted Functional Partners:
Cseg_0695
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.997
Cseg_2655
KEGG: ccr:CC_1551 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
  
 
 0.997
folE
TIGRFAM: GTP cyclohydrolase I; KEGG: ccs:CCNA_00491 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.
  
  
 0.972
Cseg_0519
KEGG: cak:Caul_0348 alkaline phosphatase; PFAM: Alkaline phosphatase D-related.
     
 0.914
Cseg_2639
KEGG: ccs:CCNA_01636 alkaline phosphatase; PFAM: Alkaline phosphatase D-related.
     
 0.914
Cseg_1675
KEGG: cak:Caul_3027 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
Cseg_0579
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ccs:CCNA_00422 3-oxoacyl-(acyl-carrier protein) reductase.
 
     0.817
Cseg_0144
TIGRFAM: FolC bifunctional protein; KEGG: ccs:CCNA_03655 folylpolyglutamate synthase/dihydrofolate synthase; PFAM: Mur ligase middle domain protein; Belongs to the folylpolyglutamate synthase family.
  
  
 0.684
ispDF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
  
  
 0.640
Cseg_0577
KEGG: ccs:CCNA_00420 hypothetical protein.
       0.605
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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