STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_0608Two component, sigma54 specific, transcriptional regulator, Fis family; KEGG: ccs:CCNA_03424 AAA-family response regulator TacA; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase. (486 aa)    
Predicted Functional Partners:
Cseg_4064
Transcriptional regulator, Fis family; PFAM: GAF domain protein; helix-turn-helix Fis-type; KEGG: ccs:CCNA_03694 transcriptional regulator.
 
    
 0.809
Cseg_4084
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.785
Cseg_0607
KEGG: ccs:CCNA_03425 hypothetical protein.
       0.773
Cseg_3175
KEGG: ccs:CCNA_01132 sensory transduction histidine kinase/receiver protein CckA; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
 
 
 0.764
Cseg_1981
Signal transduction histidine kinase, nitrogen specific, NtrB; KEGG: ccs:CCNA_01814 nitrogen regulation protein NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
 0.715
Cseg_2797
KEGG: ccs:CCNA_02547 response regulator receiver protein DivK; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.679
Cseg_3195
Integral membrane sensor signal transduction histidine kinase; KEGG: ccs:CCNA_01116 histidine protein kinase DivJ; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
 
 0.678
Cseg_3466
KEGG: bxe:Bxe_B0221 GAF sensor hybrid histidine kinase; PFAM: HWE histidine kinase; MASE1 domain protein; GAF domain protein; SMART: GAF domain protein.
  
 
 0.660
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
  
  
 0.617
Cseg_1369
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.616
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.