STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrQFerric reductase domain protein protein transmembrane component domain protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for re [...] (210 aa)    
Predicted Functional Partners:
msrP
Oxidoreductase molybdopterin binding protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to [...]
 
  
 0.996
Cseg_1075
Hydroxyisourate hydrolase; KEGG: ccs:CCNA_02703 urate oxidase; TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
   
    0.676
Cseg_1020
KEGG: ccs:CCNA_02836 hypothetical protein.
       0.572
Cseg_1021
KEGG: ccs:CCNA_02835 hypothetical protein.
       0.572
Cseg_1019
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: ccs:CCNA_02837 RNA polymerase ECF-type sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2.
       0.549
Cseg_0664
PFAM: protein of unknown function DUF692; KEGG: cak:Caul_0757 hypothetical protein; Belongs to the UPF0276 family.
 
  
 0.526
Cseg_1018
KEGG: ccs:CCNA_02838 EF hand domain protein; PFAM: EF-Hand domain; SMART: Calcium-binding EF-hand-containing protein.
       0.488
Cseg_2056
PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: cak:Caul_2954 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
   
 0.485
Cseg_0662
PFAM: DoxX family protein; KEGG: ccs:CCNA_03366 DoxX family protein.
  
  
 0.456
Cseg_4229
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ccs:CCNA_03875 quinone oxidoreductase.
     
 0.435
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.