STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_1050TIGRFAM: serine O-acetyltransferase; KEGG: ccs:CCNA_02734 serine acetyltransferase; PFAM: serine acetyltransferase domain protein; transferase hexapeptide repeat containing protein. (279 aa)    
Predicted Functional Partners:
Cseg_4112
KEGG: ccs:CCNA_03740 cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.
 
 0.991
Cseg_2468
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: hne:HNE_0181 cysteine synthase/cystathionine beta-synthase family protein.
 
 0.990
Cseg_1907
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ccs:CCNA_01493 cysteine synthase.
 
 0.984
cysS
TIGRFAM: cysteinyl-tRNA synthetase; KEGG: ccs:CCNA_00492 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.972
Cseg_0852
TIGRFAM: L-serine dehydratase 1; KEGG: ccs:CCNA_03206 L-serine dehydratase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.914
Cseg_1328
TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: ccs:CCNA_02182 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase.
    
 0.848
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.847
Cseg_1683
KEGG: ccs:CCNA_01447 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein.
     
 0.825
Cseg_4124
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
 0.825
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.818
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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