STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_1605PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ccs:CCNA_01375 lactoylglutathione lyase. (145 aa)    
Predicted Functional Partners:
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
 
  
 0.963
Cseg_2697
KEGG: ccs:CCNA_01241 Zn-dependent hydrolase, glyoxalase II family.
     
 0.909
Cseg_4124
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 0.834
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.821
Cseg_3018
PFAM: alanine racemase domain protein; KEGG: mlo:mll6666 D-serine deaminase.
   
 
  0.805
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
Cseg_0852
TIGRFAM: L-serine dehydratase 1; KEGG: ccs:CCNA_03206 L-serine dehydratase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.800
Cseg_0980
PFAM: amine oxidase; KEGG: ccs:CCNA_02883 amine oxidase (flavin-containing).
     
  0.800
Cseg_1163
PFAM: amine oxidase; KEGG: ccs:CCNA_01145 amine oxidase (flavin-containing).
     
  0.800
Cseg_1604
ABC transporter related protein; KEGG: ccs:CCNA_01374 Fe-S cluster assembly ABC-type transport system, permease and ATPase components; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase.
       0.613
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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