STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_1656PFAM: ROSMUCR transcriptional regulator; KEGG: ccs:CCNA_01418 transcriptional regulator. (148 aa)    
Predicted Functional Partners:
Cseg_1315
PFAM: protein of unknown function DUF1321; KEGG: ccs:CCNA_02187 hypothetical protein.
  
     0.624
Cseg_0148
TIGRFAM: double-strand break repair protein AddB; KEGG: ccs:CCNA_03651 ATP-dependent nuclease subunit B.
  
     0.583
Cseg_0604
PFAM: Protein of unknown function DUF2312; KEGG: ccs:CCNA_03428 cytosolic protein; Belongs to the UPF0335 family.
  
     0.555
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.555
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
     0.537
fliE
KEGG: ccs:CCNA_01006 flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE.
  
     0.505
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
    0.477
Cseg_1667
PFAM: protein of unknown function DUF177; KEGG: ccs:CCNA_01430 hypothetical protein.
  
     0.477
Cseg_1613
PFAM: Protein of unknown function DUF2497; KEGG: ccs:CCNA_01380 pole-organizing protein PopZ.
  
     0.465
Cseg_1665
PFAM: SmpA/OmlA domain protein; KEGG: ccs:CCNA_01427 lipoprotein, SmpA/OmlA family.
  
     0.455
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.