STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_1789PFAM: Luciferase-like, subgroup; KEGG: ccs:CCNA_01227 nitrilotriacetate monooxygenase. (354 aa)    
Predicted Functional Partners:
Cseg_1790
PFAM: isochorismatase hydrolase; KEGG: cak:Caul_1793 isochorismatase hydrolase.
 
 
  0.988
rutB
Pyrimidine utilization protein B; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2; Belongs to the isochorismatase family. RutB subfamily.
 
 
  0.975
Cseg_1730
KEGG: bxe:Bxe_A1380 putative oxygenase; manually curated; PFAM: flavin reductase domain protein FMN-binding.
 
 
 0.937
rutA
Pyrimidine utilization protein A; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate.
  
  
 
0.913
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
  0.900
Cseg_1791
KEGG: cak:Caul_1794 hypothetical protein.
 
     0.895
Cseg_1788
PFAM: major facilitator superfamily MFS_1; KEGG: cak:Caul_1791 major facilitator transporter.
 
    0.845
Cseg_1793
KEGG: cak:Caul_1796 taurine dioxygenase; PFAM: Taurine catabolism dioxygenase TauD/TfdA.
 
  
 0.806
Cseg_1792
PFAM: flavin reductase domain protein FMN-binding; KEGG: cak:Caul_1795 flavin reductase domain-containing protein.
 
  
 0.794
Cseg_1794
PFAM: NAD-dependent epimerase/dehydratase; KEGG: cak:Caul_1797 NAD-dependent epimerase/dehydratase.
       0.674
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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