STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_1856KEGG: ccs:CCNA_01666 osmosensitive K+ channel histidine kinase KdpD; PFAM: Osmosensitive K channel His kinase sensor; UspA domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (892 aa)    
Predicted Functional Partners:
Cseg_1857
Two component transcriptional regulator, winged helix family; KEGG: ccs:CCNA_01667 two-component response regulator KdpE; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 0.996
kdpC
Potassium-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.989
kdpB
K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.983
kdpA
Potassium-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.976
Cseg_3466
KEGG: bxe:Bxe_B0221 GAF sensor hybrid histidine kinase; PFAM: HWE histidine kinase; MASE1 domain protein; GAF domain protein; SMART: GAF domain protein.
  
 
 0.806
Cseg_3981
Non-specific serine/threonine protein kinase; Manually curated; KEGG: mch:Mchl_0020 putative circadian clock protein, KaiC; PFAM: KaiA binding.
   
 
 0.677
Cseg_1034
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; response regulator receiver; KEGG: ccs:CCNA_02752 GAF/PAS-family histidine kinase/receiver protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; response regulator receiver.
  
 
0.604
Cseg_3213
KEGG: swi:Swit_5353 multi-sensor hybrid histidine kinase; PFAM: CHASE3 domain protein; GAF domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; response regulator receiver.
  
 
0.546
Cseg_2918
KEGG: cak:Caul_5316 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; MASE1 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
  
 
0.440
Cseg_0173
Two component transcriptional regulator, winged helix family; KEGG: ccs:CCNA_00237 two-component response regulator ChvI; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
  
 
 0.427
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.