STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_2592PFAM: TrkA-N domain protein; Ion transport 2 domain protein; KEGG: ccs:CCNA_01688 potassium channel protein. (348 aa)    
Predicted Functional Partners:
rlmE
Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
       0.785
Cseg_0054
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: ccs:CCNA_00016 molybdopterin converting factor, large subunit.
   
    0.747
Cseg_2588
PFAM: Fmu (Sun) domain protein; KEGG: ccs:CCNA_01691 16S rRNA m(5)C 967 methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
    0.697
Cseg_0064
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
    0.692
Cseg_3916
KEGG: cak:Caul_4672 potassium efflux system protein; TIGRFAM: potassium efflux system protein; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
 0.607
Cseg_3914
PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; KEGG: ccs:CCNA_03611 glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
 0.592
Cseg_0100
Sun protein; KEGG: ccs:CCNA_00101 16S rRNA m5C methyltransferase RsmB; TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
    0.566
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.563
Cseg_3948
KEGG: ccs:CCNA_00204 glutathione-regulated potassium-efflux system protein KefB; TIGRFAM: potassium efflux system protein; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
0.529
Cseg_0103
KEGG: cak:Caul_4209 ATPase, P-type (transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase.
  
  
 0.516
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
Server load: medium (72%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.