STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_2629PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ccs:CCNA_01645 3-hydroxyisobutyrate dehydrogenase. (284 aa)    
Predicted Functional Partners:
Cseg_2930
KEGG: ccs:CCNA_02357 malonate-semialdehyde dehydrogenase (acetylating)/methylmalonate-semialdehyde dehydrogenase (acylating); TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase.
 
 
 0.933
Cseg_1654
TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; KEGG: ccs:CCNA_01416 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; Belongs to the HIBADH-related family.
  
  
 
0.921
Cseg_0581
PFAM: Aldehyde Dehydrogenase; KEGG: ccs:CCNA_00424 aldehyde dehydrogenase.
  
 
 0.914
Cseg_2668
PFAM: Aldehyde Dehydrogenase; KEGG: ccs:CCNA_01274 piperideine-6-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.914
Cseg_0811
PFAM: aminotransferase class-III; KEGG: ccs:CCNA_03245 omega-amino acid-pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.900
Cseg_2829
PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; KEGG: ccs:CCNA_02261 propionyl-CoA carboxylase biotin-containing subunit.
  
 
  0.823
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.820
Cseg_1538
PFAM: carboxyl transferase; KEGG: ccs:CCNA_02054 propionyl-CoA carboxylase carboxyltransferase subunit.
  
 
  0.804
Cseg_0668
Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
 
    0.609
Cseg_2355
KEGG: ccs:CCNA_02494 3-oxoadipate enol-lactonase/4-carboxymuconolactone decarboxylase; TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: Carboxymuconolactone decarboxylase; alpha/beta hydrolase fold.
  
  
 0.606
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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