STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (118 aa)    
Predicted Functional Partners:
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 0.999
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.981
Cseg_0811
PFAM: aminotransferase class-III; KEGG: ccs:CCNA_03245 omega-amino acid-pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.915
Cseg_0581
PFAM: Aldehyde Dehydrogenase; KEGG: ccs:CCNA_00424 aldehyde dehydrogenase.
    
 0.905
Cseg_2668
PFAM: Aldehyde Dehydrogenase; KEGG: ccs:CCNA_01274 piperideine-6-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.905
Cseg_3423
KEGG: ccs:CCNA_03007 L-aspartate oxidase; TIGRFAM: L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
    
 0.837
Cseg_1459
PFAM: aminotransferase class I and II; KEGG: ccs:CCNA_01603 aspartate aminotransferase.
    
 0.819
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.813
pyrB
KEGG: ccs:CCNA_02525 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
    
  0.802
Cseg_0092
PFAM: peptidase T2 asparaginase 2; KEGG: ccs:CCNA_00096 L-asparaginase.
     
  0.800
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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