STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_3059PFAM: nitrogen regulatory protein P-II; KEGG: pzu:PHZ_c1361 nitrogen regulatory protein P-II-2; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
Cseg_1635
KEGG: ccs:CCNA_01399 ammonium transporter/methylammonium transporter; TIGRFAM: ammonium transporter; PFAM: ammonium transporter.
 
 
 0.933
Cseg_1981
Signal transduction histidine kinase, nitrogen specific, NtrB; KEGG: ccs:CCNA_01814 nitrogen regulation protein NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
  
 
 0.725
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.686
Cseg_4092
KEGG: ccs:CCNA_03722 glutamate synthase (NADPH) large chain; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein.
  
  
 0.655
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 
 0.642
Cseg_1372
PFAM: Tetratricopeptide TPR_4; KEGG: ccs:CCNA_02137 endoglucanase H.
    
 
 0.629
Cseg_1616
Beta-lactamase; KEGG: sml:Smlt0115 putative beta-lactamase precursor (cephalosporinase); PFAM: beta-lactamase; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide repeat.
    
 
 0.629
Cseg_2546
KEGG: kko:Kkor_1250 hypothetical protein.
    
 
 0.629
Cseg_3338
PFAM: protein of unknown function DUF897; KEGG: ccs:CCNA_03624 sodium bicarbonate cotransporter.
   
 
 0.545
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.523
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.