STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_3242KEGG: mdi:METDI2604 hypothetical protein. (845 aa)    
Predicted Functional Partners:
Cseg_3241
KEGG: mdi:METDI2603 putative AAA ATPase; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.
 
    0.924
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.651
Cseg_4213
PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; KEGG: ccs:CCNA_03819 cell division protein FtsK.
  
 
 0.587
Cseg_3726
PFAM: Surfeit locus 1 family protein; KEGG: ccs:CCNA_01847 cytochrome c oxidase assembly protein SURF1.
  
 
   0.585
Cseg_1433
Peptidase M23; KEGG: ccs:CCNA_02075 peptidoglycan-specific endopeptidase, M23 family; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
  
  
 0.548
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
     
 0.543
Cseg_0290
KEGG: ccs:CCNA_03511 cytochrome c oxidase assembly protein SURF1.
    
   0.528
Cseg_0103
KEGG: cak:Caul_4209 ATPase, P-type (transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase.
   
 0.521
Cseg_0875
KEGG: pzu:PHZ_c2479 hypothetical protein.
  
 
 0.521
Cseg_1274
PFAM: Hemolysin-type calcium-binding region; KEGG: pol:Bpro_4929 hemolysin-type calcium-binding region.
  
 
 0.521
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.