STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_3433Leucyl aminopeptidase; KEGG: ccs:CCNA_03032 cytosol aminopeptidase; PFAM: peptidase M17 leucyl aminopeptidase domain protein. (468 aa)    
Predicted Functional Partners:
gshB
TIGRFAM: glutathione synthetase; KEGG: ccs:CCNA_00140 glutathione synthetase; PFAM: glutathione synthetase ATP-binding; glutathione synthetase domain protein; Belongs to the prokaryotic GSH synthase family.
   
 
 0.925
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
 
  
 
0.921
Cseg_1258
KEGG: ccs:CCNA_02566 membrane alanine aminopeptidase; TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase.
  
 0.918
Cseg_0411
TIGRFAM: gamma-glutamyltransferase; KEGG: ccs:CCNA_00565 gamma-glutamyltranspeptidase; PFAM: gamma-glutamyltranspeptidase.
     
 0.914
Cseg_0274
Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
     
  0.900
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.826
Cseg_1907
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ccs:CCNA_01493 cysteine synthase.
   
 0.823
Cseg_2468
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: hne:HNE_0181 cysteine synthase/cystathionine beta-synthase family protein.
   
 0.823
Cseg_4112
KEGG: ccs:CCNA_03740 cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.
   
 0.823
Cseg_1459
PFAM: aminotransferase class I and II; KEGG: ccs:CCNA_01603 aspartate aminotransferase.
   
  0.817
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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