STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_3705Cytidyltransferase-related domain protein; KEGG: xcv:XCV0734 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; TIGRFAM: cytidyltransferase-related domain protein; PFAM: NUDIX hydrolase; cytidylyltransferase; Belongs to the Nudix hydrolase family. (346 aa)    
Predicted Functional Partners:
Cseg_3704
KEGG: sml:Smlt0260 putative nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; Belongs to the NAPRTase family.
 
  
 0.992
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.964
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.944
Cseg_3424
TIGRFAM: nicotinate-nucleotide pyrophosphorylase; KEGG: ccs:CCNA_03009 nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
    
 0.944
Cseg_1324
PFAM: CinA domain protein; KEGG: cak:Caul_3350 CinA domain-containing protein; Belongs to the CinA family.
    
 0.928
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.926
Cseg_3891
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: ccs:CCNA_00267 MutT-like protein; Belongs to the Nudix hydrolase family.
    
0.913
Cseg_0620
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
    
  0.901
Cseg_0618
NAD(P)(+) transhydrogenase (AB-specific); KEGG: ccs:CCNA_03414 NAD(P) transhydrogenase alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein.
     
  0.900
Cseg_0619
KEGG: ccs:CCNA_03413 NAD(P) transhydrogenase alpha subunit.
     
  0.900
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.