STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_3852PFAM: protein of unknown function DUF374; KEGG: cak:Caul_4539 hypothetical protein. (232 aa)    
Predicted Functional Partners:
Cseg_3854
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
     0.983
Cseg_2901
PFAM: lipid A biosynthesis acyltransferase; KEGG: ccs:CCNA_02333 lipid A biosynthesis lauroyl acyltransferase.
 
  
  0.961
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
     0.854
Cseg_3851
ABC transporter related protein; KEGG: ccs:CCNA_00307 phospholipid-lipopolysaccharide ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase.
 
     0.839
Cseg_3853
Cation diffusion facilitator family transporter; KEGG: ccs:CCNA_00305 cobalt-zinc-cadmium resistance protein CzcD; TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein.
       0.688
Cseg_3850
Protein tyrosine/serine phosphatase; KEGG: ccs:CCNA_00308 hypothetical protein.
       0.613
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
     0.587
Cseg_2197
PFAM: protein of unknown function DUF1009; KEGG: ccs:CCNA_01987 hypothetical protein.
 
     0.580
lpxA
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
     0.551
Cseg_3123
PFAM: MotA/TolQ/ExbB proton channel; KEGG: ccs:CCNA_02421 TonB accessory protein ExbB.
 
     0.544
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.